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ELSD detectors are univerzal detectors which measures sample particles after solvent evaporation by using scattered light. This kind of detection is independent of optical properties of sample in contrast to UV detection. Analyte must be lower volatile than solvent. It is possible to detect compounds without chromophores like: saccharides, lipids, polymers, non-derivatized fat acids and amino acids, oils, surface active compounds, small molecules and unknown compounds whitout information about their structure. Response of detector is depending on quantity and it is mean that detector can be used for quantitative analysis without calibration. It can be used in gradient applications and it not depend on temperature in contrast of RI detectors.
- low evaporation temperature settings
- choice of two nebulizers
- easy validation and calibration
- automated operations
Source of nebulizing gas is neccessary for detector operation. Air pressure can be used as nebulizing gas for non-explosive and on higher used temperature safe solvents (it can not be used for explosive THF and for solvents with higher fraction of organics). Air pressure can not be used for samples degrading by oxidation. Nitrogen is solution for other cases. Pressure cylinders can be used as gas source (expensive) or gas generators - see to accessories.
Next items is neccessary to order with detector: Gas regulator with filter and manometer for ELSD (for generator and pressure cylinder also).
This detector is equiped with HPLC nebulizer, but on request could be equiped with CC nebulizer see nebulizers flow-rates overview.
|Info-SEDEX80LT_detector-en.pdf||pdf (79,33 KB)|